Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free: https://www.ghostery.com/fr/products/

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site: http://www.youronlinechoices.com/fr/controler-ses-cookies/, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Realytics
Google Analytics
Spoteffects
Optimizely

Targeted advertising cookies

DoubleClick
Mediarithmics

The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at cil-dpo@inra.fr or by post at:

INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal logo Université Clermont Auvergne & associés

Human Nutrition Unit

Zone de texte éditable et éditée et rééditée

Our Publications 2018 and 2019

Original Publications and Reviews 2019

Poupin N, M Tremblay-Franco, A Amiel, C Canlet, D Rémond, L Debrauwer, D Dardevet, I Thiele, MK. Aurich, F Jourdan, I Savary-Auzeloux, S Polakof Arterio-venous metabolomics exploration reveals major changes across liver and intestine in the obese minipig  Scientific Reports 

Duconseille A, François O, Pereira B, Lambert C, Peyron MA, Hennequin M. Measuring the effects of in vitro mastication on bolus granulometry of shredded meat : a proposal for a new methdodological procedure. Food Research International,

Peyron MA, Santé-Lhoutellier, D.Dardevet, M.Hennequi, D.Rémond, O.François, A.Woda. Addressing various challenges related to food bolus and nutrition with the AM2 mastication simulator. Food Hydrocolloids

Correa-Pérez A, Abraha I, Cherubini A, Collinson A, Dardevet D, de Groot LC, de van der Schueren MAE, Hebestreit A, Hickson M, Jaramillo-Hidalgo J, Lozano-Montoya I, O'Mahony D, Soiza RL, Visser M, Volkert D, Wolters M, Jentoft AJC. Efficacy of non-pharmacological interventions to treat malnutrition in older persons: A systematic review and meta-analysis. The SENATOR project ONTOP series and MaNuEL Knowledge Hub project. Ageing Res Rev.

O'Keeffe M, Kelly M, O'Herlihy E, O'Toole PW, Kearney PM, Timmons S, O'Shea E, Stanton C, Hickson M, Rolland Y, Sulmont Rossé C, Issanchou S, Maitre I, Stelmach-Mardas M, Nagel G, Flechtner-Mors M, Wolters M, Hebestreit A, De Groot LCPGM, van de Rest O, Teh R, Peyron MA, Dardevet D, Papet I, Schindler K, Streicher M, Torbahn G, Kiesswetter E, Visser M, Volkert D, O'Connor EM; MaNuEL consortium.Potentially modifiable determinants of malnutrition in older adults: A systematic review. Clinical  Nutrition.

Mosoni L, M Jarzaguet, J David, S Polakof, I Savary-Auzeloux, D Rémond and D Dardevet. Post Meal Energy Boluses Do Not Increase the Duration of Muscle Protein Synthesis Stimulation in Two Anabolic Resistant Situations.  Nutrients 2019

Le Bacquer O, Combe K, Patrac V, Ingram B, Combaret L, Dardevet D, Montaurier C, Salles J, Giraudet C, Guillet C, Sonenberg N, Boirie Y, Walrand S. 4E-BP1 and 4E-BP2 double knockout mice are protected from aging-associated sarcopenia. J Cachexia Sarcopenia Muscle.2019 Mar 29. doi: 10.1002/jcsm.12412.

Linas N, Peyron MA, Hennequin M, Eschevins C, Nicolas E, Delfosse C, Collado V. Masticatory behavior for different solid foods in preschool children according to their oral state. J Texture Stud

David J, D Dardevet; L Mosoni; I Savary-Auzeloux; S Polakof Impaired skeletal muscle branched-chain amino acids catabolism contributes to their increased circulating levels in a non-obese insulin resistant fructose-fed rat model. Nutrients

Savary-Auzeloux I., Mohamed A.B., Cohade B., Dardevet D., David J., Hafnaoui N., Migne  C. , Pujos-Guillot E., Rémond D.1, Polakof S. Overfeeding of Yucatan mini pigs altered greatly the net energy and nitrogen metabolites fluxes within and between the splanchnic and peripheral tissues to limit hyperglycemia Nutrients

Original Publications and Reviews 2018

Mohamed AB, D Rémond, C Chambon, T Sayd, M Hebraud, F Capel, B Cohade, N Hafnaoui, D Bechet, C Coudy-Gandilhon, C Migné, J David, D Dardevet, J Doré, S Polakof, I Savary-Auzeloux.    A mix of dietary fibers improves lipids handling by the liver of overfed minipigs   Journal of Nutritional Biochemistry

Zeng Y, J David, D Rémond, D Dardevet, I Savary-Auzeloux, S Polakof. Peripheral blood mononuclear cells metabolism adapted acutely to the postprandial transition and reflected mainly the adipose tissue metabolic adaptations to a high fat fed diet in minipigs. Nutrients, 2018

Jarzaguet M,  S Polakof,  J David,  C Migné,  G Joubrel,  T Efstathiou,  D Remond,  L Mosoni,   D Dardevet A meal with mixed soy/whey proteins is as efficient as a whey meal in counteracting the aged-related muscle anabolic resistance only if protein content and leucine levels are increased.Food &Function. 2018

Xia Z, J. M. Cholewa, D. Dardevet, T. Huang, Y. Zhao, H. Shang, Y. Yang,  X. Ding, C.  Zhang, H. Wang, S. Liu, Q. Su and N. E. Zanchi. Effects of oats protein supplementation on skeletal muscle damage, inflammation and performance recovery following downhill running in untrained collegiate men. Food &Function. 2018

Pujos-Guillot E, Brandolini-Bunlon M, Fouillet H, Joly C, Martin JF, Huneau JF, Dardevet D, Mariotti F. Metabolomics Reveals that the Type of Protein in a High-Fat Meal Modulates Postprandial Mitochondrial Overload and Incomplete Substrate Oxidation in Healthy Overweight Men. J Nutr. 2018

Bidu C, S Bellenger, A Spor, M Galan, A Geissler, D Dardevet, B Morio-LiondorE, Cani, L Lagrost, M Narce, J Bellenger. The transplantation of w3 PUFA-altered gut microbiota of fat-1 mice to wild-type littermates prevents obesity and associated metabolic disorders. Diabetes 2018 

Gatineau E,  Cluzet S,  Krisa S, Papet I,   Migné C,   Rémond D,  Dardevet D,  Polakof S,  Richard T  and Mosoni L. Effect of nutritional state, aging and high chronic intake of sucrose on brain protein synthesis in rats, Modulation by rutin and other micronutrients. Food&Function , 2018

Margier M, Buffière C, Goupy P, Rémond D, Halimi C, Caris C, Borel P, Reboul E. Opposite effects of the spinach food matrix on lutein bioaccessibility and intestinal uptake lead to unchanged bioavailability compared to pure lutein. Mol Nutr Food Res. 2018 

Gatineau E, S Cluzet, S Krizac, I Papet C Migné, D Rémond, D Dardevet, S Polakof, T Richard, L Mosoni.  Effect of high chronic intake of sucrose on liver metabolism in aging rats. Modulation by rutin and micronutrients. Journal of Physiology and Biochemistry, 2018. 

Mast C, Dardevet D, Papet I. Impact of medication on protein and amino acid metabolism in the elderly: the sulfur amino acid and paracetamol case. Nutr Res Rev. 2018

Polakof S, Rémond D, Bernalier-Donadille A, Rambeau M, Pujos-Guillot E, Comte B, Dardevet D, Savary-Auzeloux I. Metabolic adaptations to HFHS overfeeding: how whole body and tissues postprandial metabolic flexibility adapt in Yucatan mini-pigs. Eur J Nutr. 2018

Dufour C, Loonis M, Delosière M, Buffière C, Hafnaoui N, Santé-Lhoutellier V, Rémond D. The matrix of fruit & vegetables  modulates the gastrointestinal bioaccessibility of polyphenols and their impact on dietary protein digestibility. Food Chem, 2018

Peyron MA , Santé-Lhoutellier V , François O , Hennequin M .Oral declines and mastication deficiencies cause alteration of food bolus properties. Food Funct , 2018

Dardevet D, Mosoni L, David J, Polakof S. Fructose Feeding during the Postabsorptive State Alters Body Composition and Spares Nitrogen in Protein-Energy-Restricted Old Rats. J Nutr. 2018

Sayd  T, C. Dufour, C. Chambon, C. Buffière,  D.Remond,  V.Santé-Lhoutellier Combined in vivo and in silico approaches for predicting the release of bioactive peptides from meat digestion. Food Chemistry  2018

Polakof S, D Rémond, J David, D Dardevet, I Savary-Auzeloux. Time-course changes in circulating branched-chain amino acid levels and metabolism in obese Yucatan minipig.  Nutrition 2018

Mantha O, S. Polakof, J.F. Huneau, F. Mariotti, N. Poupin, D. Zalko, H Fouillet. Early changes in tissue amino acid metabolism and nutrient routing in rats fed a high-fat diet: evidence from natural isotope abundances as biomarkers. British Journal of Nutrition, 2018.

Zabek A, Paslawski R, Paslawska U, Wojtowicz W, Drozdz K, Polakof S, Podhorska M, Dziegiel P, Mlynarz P, Szuba A  The influence of different diets on metabolism and atherosclerosis processes - a porcine model. Blood serum, urine and tissues 1H NMR metabolomics targeted analysis. 2017, PlosONE

Barquissau, V ; F Capel.; D Dardevet; C Feillet-Coudray; A Gallinier.; MA Chauvin; J Rieusset; B Morio.Reactive oxygen species enhance mitochondrial function, insulin sensitivity and glucose uptake in skeletal muscle of senescence accelerated prone mice SAMP8. 2017,  Free Radical Biology and Medicine

Revel A, M Jarzaguet, MA Peyron, I Papet, N Hafnaoui, C Migné, L Mosoni, S Polakof, I Savary-Auzeloux, D Rémond and D Dardevet. At same leucine intake, a whey/plant protein blend is not as effective as whey to initiate a transient post prandial muscle anabolic response during a catabolic state in mini pigs. 2017, PlosONE

Buffière C, C Gaudichon, N Hafnaoui, C Migné, V Scislowsky, N Khodorova, L Mosoni, A Blot, Y Boirie, D Dardevet, V Santé-Lhoutellier, D Rémond. In the elderly, meat protein assimilation from rare meat is lower than that from meat that is well done. 2017, American Journal of Clinical Nutrition

Mast C., C. Pourpre, G. Voyard , D. Rémond, C. Migné, D. Centeno, D. Dardevet, I. Savary-Auzeloux  and I. Papet. Dietary supplementation with cysteine prevents adverse metabolic outcomes of repeated cures with paracetamol in old rats. 2017, British Journal of Nutrition

Louessard M, Bardou I, Lemarchand E, Thiebaut AM, Parcq J, Leprince J, Terrisse A, Carraro V, Fafournoux P, Bruhat A, Orset C, Vivien D, Ali C, Roussel BD. Activation of cell surface GRP78 decreases endoplasmic reticulum stress and neuronal death. 2017 Cell Death Differ. Sep;24(9):1518-1529.

Mesclon F, Lambert-Langlais S, Carraro V, Parry L, Hainault I, Jousse C, Maurin AC, Bruhat A, Fafournoux P, Averous J. Decreased ATF4 expression as a mechanism of acquired resistance to long-term amino acid limitation in cancer cells. 2017 Oncotarget Apr 18;8(16):27440-27453.

Bruhat A, Fafournoux P. The CCAAT/enhancer-binding protein-ATF response elements-luciferase mouse model, an innovative tool to monitor the integrated stress response pathway in vivo. 2017 Curr Opin Clin Nutr Metab Care May;20(3):175-180.

Bruhat A, Chaveroux C, Carraro V, Jousse C, Averous J, Maurin AC, Parry L, Mesclon F, Muranishi Y, Baril P, Do Thi A, Ravassard P, Mallet J, Fafournoux P. [Tuning transgene expression with an artificial diet: a compelling resource in gene therapy]. 2017 Med Sci (Paris) Feb;33(2):136-139.

Dumortier O, Roger E, Pisani DF, Casamento V, Gautier N, Lebrun P, Johnston H, Lopez P, Amri EZ, Jousse C, Fafournoux P, Prentki M, Hinault C, Van Obberghen E. Age-Dépendent Control of Energy Homeostasis by Brown Adipose Tissue in Progeny Subjected to Maternal Diet-Induced Fetal Programming.  2017 Diabètes Mar;66(3):627-639.

Cholewa J,  D DardeveT,  Lima Soares F, , K Pessôa, PH Oliveira,  J R Dos Santos Pinho, H Nicastro, Z Xia, C Emmanuel Torres Cabido,NE Zanchi. Dietary proteins and amino acids in the control of the muscle mass during immobilization and aging: Role of the MPS response. 2017 Aminoacids  May;49(5):811-820 

Gatineau E, S Polakof, D Dardevet, L Mosoni. Similarities and interactions between the aging process and high chronic intake of added sugars. Nutrition Research Reviews, 2017 17:1-17

BORDONI A, F DANESI, D DARDEVET, D GILLE, L AUTHOR, C NUNES DOS SANTOS, P PINTO, R RE, D REMOND, D SHAKAR, G VERGÈRES. Dairy Products and Inflammation: A Review of the Clinical Evidence Crit Rev Food Sci Nutr. 2017, 57, 2497-2525  

Arufe S, Chiron H, Doré J, Savary-Auzeloux I, Saulnier L, Della Valle G. Processing and rheological properties of wheat flour dough and bread containing high levels of soluble fibres blends. Food research International. 2017 Jul;97:123-132  

Kraft G, KC. Coate,  J Winnick, D Dardevet, PE. Donahue, AD. Cherrington, PE. Williams and MC Moore. Glucagon’s effect on liver protein metabolism in vivo. American Journal of Physiology.  May 23:ajpendo.00045.2017.

Verney J, V Martin, S Ratel, V Chavanelle, M Bargetto,M Etienne, E Chaplais, P Le Ruyet, C Bonhomme, L Combaret, C Guillet, N Boisseau, P Sirvent and D Dardevet. Soluble milk proteins improve muscle mass recovery after immobilization-induced muscle atrophy in old rats but do not improve muscle functional property restoration. The journal of Nutrition, Health & Aging. 2017

Bohn T, Carriere F, Day L, Deglaire A, Egger L, Freitas D, Golding M, Le Feunteun S,Macierzanka A, Menard O, Miralles B, Moscovici A, Portmann R, Recio I, Rémond D, Santé-Lhoutelier V, Wooster TJ, Lesmes U, Mackie AR, Dupont D. Correlation between in vitro and in vivo data on food digestion. What can we predict with static in vitro digestion models? Crit Rev Nutr Food Sci 2017

Thorning TK, Bertram HC, Bonjour JP, de Groot L, Dupont D, Feeney E, Ipsen R, Lecerf JM, Mackie A, McKinley M, Michalski MC, Rémond D, Risérus U, Soedamah-Muthu S, Tholstrup T, Weaver C, Astrup A, Givens I, 2017. Whole dairy matrix or single nutrients in assessment of health effects: current evidence and knowledge gaps. Am J Clin Nutr , 2017, May;105(5):1033-1045

Chavanelle V, N Boisseau, YF Otero, L Combaret, D Dardevet, C Montaurier, G Delcros, S Peltier, P Sirvent Effects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice. Scientific reports Mar 16;7(1):204

Le Bacquer O, Combe K, Patrac V, Ingram B, Combaret L, Dardevet D, Montaurier C, Salles J, Giraudet C, Guillet C, Sonenberg N, Boirie Y, Walrand S. 4E-BP1 and 4E-BP2 double knockout mice are protected from aging-associated sarcopenia.J Cachexia Sarcopenia Muscle. 2019 Mar 29. doi: 10.1002/jcsm.12412.