Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free:

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site:, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Google Analytics

Targeted advertising cookies


The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at or by post at:

24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal logo Université Clermont Auvergne & associés

Human Nutrition Unit

Zone de texte éditable et éditée et rééditée

Scientific production

ACL : Peer-reviewed articles in international and national journals listed by AERES or in international databases (ISI Web of Knowledge, PubMed,...)
1. Gao XF, Pujos-Guillot E, Sebedio JL. (2010). Development of a Quantitative Metabolomic Approach to Study Clinical Human Fecal Water Metabolome Based on Trimethylsilylation Derivatization and GC/MS Analysis. Analytical chemistry. Accepted ac-2010-006552.R2. IF5 = 5.625
2. Balage M, Averous J, Rémond D, Bos C, Pujos-Guillot E, Papet I, Mosoni L, Combaret L & Dardevet D. (2010). Presence of Low-Grade Inflammation Impaired Postprandial Stimulation of Muscle Protein Synthesis in Old Rats. Journal of Nutritional Biochemistry 21, 325-331. IF5 = 4.207.
3. Bernard L, Mouriot J, Rouel J, Glasser F, Capitan P, Pujos-Guillot E, Chardigny JM & Chilliard Y. (2010). Effects of fish oil and starch added to a diet containing sunflower-seed oil on dairy goat performance, milk fatty acid composition and in vivo Delta9-desaturation of [13C]vaccenic acid. British Journal of Nutrition doi: 10.1017/S0007114510000486 1-9. IF5 = 3.569.
4. Pereira H, Martin JF, Joly C, Sebedio JL & Pujos-Guillot E. (2010). Development and validation of a UPLC/MS method for a nutritional metabolomic study of human plasma. Metabolomics 6, 207-218. IF5 = 3.847.
5. Rémond D, Buffière C, Pouyet C, Papet I, Dardevet D, Savary-Auzeloux I, Williamson G, Faure M & Breuillé D. (2010). Cysteine fluxes across the portal-drained viscera of enterally fed minipigs: effect of an acute intestinal inflammation. Amino acids, in press. IF5 = 3.191.
6. Talvas J, Caris-Veyrat C, Guy L, Rambeau M, Lyan B, Minet-Quinard R, Lobaccaro JMA, Vasson MP, George S, Mazur A & Rock E. (2010). Differential effects of lycopene consumed in tomato paste and lycopene in the form of a purified extract on target genes of cancer prostatic cells. American Journal of Clinical Nutrition 91, 1716-1724. IF5 = 7.744.
7.Berdeaux O, Dutta P, Dobarganes M & Sebedio JL. (2009). Analytical Methods for Quantification of Modified Fatty Acids and Sterols Formed as a Result of Processing. Food Analytical Methods 2, 30-40. IF = 1.400.
8. Gao XF, Pujos-Guillot E, Martin JF, Galan P, Juste C, Jia W & Sebedio JL. (2009). Metabolite Analysis of Human Fecal Water by Gas Chromatography/Mass Spectrometry With Ethyl Chloroformate Derivatization. Analytical biochemistry 393, 163-175. IF = 3.287.
9.Pujos E, Cren-Olive C, Paisse O, Flament-Waton MM & Grenier-Loustalot MF. (2009). Comparison of the analysis of beta-blockers by different techniques. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 877, 4007-4014. IF = 2.777.
10. Sebedio JL, Pujos-Guillot E & Ferrara M. (2009). Metabolomics in Evaluation of Glucose Disorders. Current Opinion in Clinical Nutrition and Metabolic Care 12, 412-418. IF = 4.291.
11. Baccini M, Bachmaier EM, Biggeri A, Boekschoten MV, Bouwman FG, Brennan L, Caesar R, Cinti S, Coort SL, Crosley K, Daniel H, Drevon CA, Duthie S, Eijssen L, Elliott RM, van Erk M, Evelo C, Gibney M, Heim C, Horgan GW, Johnson IT, Kelder T, Kleemann R, Kooistra T, van Iersel MP, Mariman EC, Mayer C, McLoughlin G, Muller M, Mulholland F, van Ommen B, Polley AC, Pujos-Guillot E, Rubio-Aliaga I, Roche HM, de Roos B, Sailer M, Tonini G, Williams LM & de Wit N. (2008). The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation. Genes & Nutrition 3, 147-151. IF = 0.451.
12.Bretillon L, Roy A, Pasquis B & Sebedio JL. (2008). Dietary Cyclic Fatty Acids Derived From Linolenic Acid Do Not Exhibit Intrinsic Toxicity in the Rat During Gestation. Animal 2, 1534-1537. IF = 0.994.
13. Carpentier YA, Peltier S, Portois L, Sebedio JL, Leverve X & Malaisse WJ. (2008). Rapid Reduction of Liver Steatosis in Omega 3-Depleted Rats Injected With a Novel Lipid Emulsion. Hormone and Metabolic Research 40, 875-879. IF = 2.715.
14. Chanson A, Cardinault N, Rock E, Martin JF, Souteyrand P, D'Incan M & Brachet P. (2008). Decreased plasma folate concentration in young and elderly healthy subjects after a short-term supplementation with isotretinoin. Journal of the European Academy of Dermatology and Venereology 22, 94-100. IF = 2.276.
15. Chardigny JM, Destaillats F, Malpuech-Brugere C, Moulin J, Bauman DE, Lock AL, Barbano DM, Mensink RP, Bezelgues JB, Chaumont P, Combe N, Cristiani I, Joffre F, German JB, Dionisi F, Boirie Y & Sebedio JL. (2008). Do Trans Fatty Acids From Industrially Produced Sources and From Natural Sources Have the Same Effect on Cardiovascular Disease Risk Factors in Healthy Subjects? Results of the Trans Fatty Acids Collaboration (Transfact) Study. American Journal of Clinical Nutrition 87, 558-566. IF = 6.740.
16. Destaillats F, Chardigny JM, Malpuech-Brugere C, Bauman DE, Sebedio JL, Bezelgues JB & Dionisi F. (2008). Unravelling the complexity of health effects of trans fatty acids: Insight from the TRANSFACT study. Lipid Technology 20, 129-131. .
17. Fardet A, Llorach R, Martin JF, Besson C, Lyan B, Pujos-Guillot E & Scalbert A. (2008). A Liquid Chromatography-Quadrupole Time-of-Flight (Lc-Qtof)-Based Metabolomic Approach Reveals New Metabolic Effects of Catechin in Rats Fed High-Fat Diets. Journal of Proteome Research 7, 2388-2398. IF = 5.684.
18. Fardet A, Llorach R, Orsoni A, Martin JF, Pujos-Guillot E, Lapierre C & Scalbert A. (2008). Metabolomics provide new Insight on the metabolism of dietary phytochemicals in rats. Journal of Nutrition 138, 1282-1287. IF = 3.647.
19. Rayssiguier Y, Alexandre-Gouabau MC, Lyan B, Gueux E, Mazur A & Rock E. (2008). Inflammation Interferes With the Assessment of Vitamin a Status in Magnesium Deficiency. Magnesium Research 21, 237-239. IF = 2.123.
20. Sebedio JL. (2008). Physiological Effects of Trans Fatty Acids in Humans. Cab Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources 3, 12 pp. .
21. Sebedio JL, Martin JF & Pujos E. (2008). Nutritional Metabolomics: What Are the Perspectives? Ocl - Oleagineux, Corps Gras, Lipides 15, 341-345. .
22. Bauchart D, Roy A, Lorenz S, Chardigny JM, Ferlay A, Gruffat D, Sebedio JL, Chilliard Y & Durand D. (2007). Butters varying in trans 18:1 and cis-9,trans-11 conjugated linoleic acid modify plasma lipoproteins in the hypercholesterolemic rabbit. Lipids 42, 123-133. IF = 1.419.
23. Berdeaux O, Fournier V, Lambelet P, Dionisi F, Sebedio JL & Destaillats F. (2007). Isolation and Structural Analysis of the Cyclic Fatty Acid Monomers Formed From Eicosapentaenoic and Docosahexaenoic Acids During Fish Oil Deodorization. Journal of Chromatography a 1138, 216-224. IF = 3.641.
24. Borel P, Moussa M, Reboul E, Lyan B, Defoort C, Vincent-Baudry S, Maillot M, Gastaldi M, Darmon M, Portugal H, Planells R & Lairon D. (2007). Human plasma levels of vitamin E and carotenoids are associated with genetic polymorphisms in genes involved in lipid metabolism. Journal of Nutrition 137, 2653-2659. IF = 3.771.
25. Bourdiol P, Abou El Karam S, Martin JF, Nicolas E & Mioche L. (2007). Age and gender-related differences in premolar and molar functional areas. Journal of Oral Rehabilitation 34, 251-258. IF = 1.200.
26. Carpentier YA, Peltier S, Portois L, Chardigny JM, Sebedio JL, Leverve X & Malaisse WJ. (2007). Accelerated clearance of plasma triglycerides and free fatty acids in omega 3-depleted rats. Hormone and Metabolic Research 39, 295-305. IF = 2.254.
27. Chanson A, Rock E, Martin JF, Liotard A & Brachet P. (2007). Preferential response of glutathione-related enzymes to folate-dependent changes in the redox state of rat liver. European Journal of Nutrition 46, 204-212. IF = 2.098.
28. Fardet A, Canlet C, Gottardi G, Lyan B, Llorach R, Remesy C, Mazur A, Paris A & Scalbert A. (2007). Whole-grain and refined wheat flours show distinct metabolic profiles in rats as assessed by a 1H NMR-based metabonomic approach. Journal of Nutrition 137, 923-929. IF = 3.771.
29. Felgines C, Texier O, Besson C, Lyan B, Lamaison JL & Scalbert A. (2007). Strawberry pelargonidin glycosides are excreted in urine as intact glycosides and glucuronidated pelargonidin derivatives in rats. British Journal of Nutrition 98, 1126-1131. IF = 3.132.
30. Fournier V, Destaillats F, Hug B, Golay PA, Joffre F, Juaneda P, Semon E, Dionisi F, Lambelet P, Sebedio JL & Berdeaux O. (2007). Quantification of Eicosapentaenoic and Docosahexaenoic Acid Geometrical Isomers Formed During Fish Oil Deodorization by Gas-Liquid Chromatography. Journal of Chromatography a 1154, 353-359. IF = 3.641.
31. Fournier V, Destaillats F, Lambelet P, Dionisi F, Sebedio JL & Berdeaux O. (2007). Degradation Products Formed From Long-Chain Pufa During Deodorization of Fish Oil. Lipid Technology 19, 9-11. .
32. Gitenay D, Lyan B, Rambeau M, Mazur A & Rock E. (2007). Comparison of lycopene and tomato effects on biomarkers of oxidative stress in vitamin E deficient rats. European Journal of Nutrition 46, 468-475. IF = 2.098.
33. Gitenay D, Lyan B, Talvas J, Mazur A, George S, Caris-Veyrat C & Rock E. (2007). Serum from rats fed red or yellow tomatoes induces connexin43 expression independently from lycopene in a prostate cancer cell fine. Biochemical and Biophysical Research Communications 364, 578-582. IF = 2.749.
34.Juaneda P, LeDoux M & Sebedio JL. (2007). Analytical methods for determination of trans fatty acid content in food. European Journal of Lipid Science and Technology 109, 901-917. IF = 0.911.
35. LeDoux M, Juaneda P & Sebedio JL. (2007). Trans fatty acids: Definition and occurrence in foods. European Journal of Lipid Science and Technology 109, 891-900. IF = 0.911.
36. LeDoux M, Laloux L, Fontaine JJ, Carpentier YA, Chardigny JM & Sebedio JL. (2007). Rumenic Acid Significantly Reduces Plasma Levels of Ldl and Small Dense Ldl Cholesterol in Hamsters Fed a Cholesterol- and Lipid-Enriched Semi-Purified Diet. Lipids 42, 135-141. IF = 1.419.
37. Mansoor O, Breuillé D, Béchereau F, Buffière C, Pouyet C, Beaufrère B, Vuichoud J, Van't-of M & Obled C. (2007). Effect of an enteral diet supplemented with a specific blend of amino acid on plasma and muscle protein synthesis in ICU patients. Clinical Nutrition 26, 30-40. IF = 2.878.
38. Mayot G, Vidal K, Martin JF, Breuillé D, Blum S, Obled C & Papet I. (2007). Prognostic values of alpha2-macroglobulin, fibrinogen and albumin in regards to mortality and frailty in old rats. Experimental Gerontology 42, 498-505. IF = 3.008.
39. Niderkorn V, Morgavi DP, Pujos E, Tissandier A & Boudra H. (2007). Screening of fermentative bacteria for their ability to bind and biotransform deoxynivalenol, zearalenone and fumonisins in an in vitro simulated corn silage model. Food Additives and Contaminants 24, 406-415. IF = 2.045.
40. Plourde M, LeDoux M, Gregoire S, Portois L, Fontaine JJ, Carpentier YA, Angers P, Chardigny JM & Sebedio JL. (2007). Adverse Effects of Conjugated Alpha-Linolenic Acids (Clna) on Lipoprotein Profile on Experimental Atherosclerosis in Hamsters. Animal 1, 905-910.
41. Rieu I, Balage M, Sornet C, Debras E, Ripes S, Rochon-Bonhomme C, Pouyet C, Grizard J & Dardevet D. (2007). Increased availability of leucine with leucine-rich whey proteins improves postprandial muscle protein synthesis in aging rats. Nutrition 23, 323-331. IF = 2.104.
42. Walsh MC, Brennan L, Pujos-Guillot E, Sebedio JL, Scalbert A, Fagan A, Higgins DG & Gibney MJ. (2007). Influence of acute phytochemical intake on human urinary metabolomic profiles. American Journal of Clinical Nutrition 86, 1687-1693. IF = 7.207.
43. Bretillon L, Loreau O, Sebedio JL & Taran F. (2006). In vivo oxidation of [9-C-14] cyclic fatty acids derived from linolenic acid in the rat. Reproduction, Nutrition, Development 46, 189-193. IF = 1.817.
44. Breuillé D, Béchereau F, Buffière C, Denis P, Pouyet C & Obled C. (2006). Beneficial effect of amino acid supplementation, especially cysteine, on body nitrogen economy in septic rats. Clinical Nutrition 25, 634-642. IF = 2.474.
45. Chamba JF, Chardigny JM, Gnadig S, Perreard E, Chappaz S, Rickert R, Steinhart H & Sebedio JL. (2006). Conjugated linoleic acid (CLA) content of french emmental cheese: effect of the season, region of production, processing and culinary preparation. Lait 86, 461-467. IF = 0.868.
46. Fournier V, Destaillats F, Juaneda P, Dionisi F, Lambelet P, Sebedio JL & Berdeaux O. (2006). Thermal degradation of long-chain polyunsaturated fatty acids during deodorization of fish oil. European Journal of Lipid Science and Technology 108, 33-42. IF = 1.184.
47. Fournier V, Juaneda P, Destaillats F, Dionisi F, Lambelet P, Sebedio JL & Berdeaux O. (2006). Analysis of Eicosapentaenoic and Docosahexaenoic Acid Geometrical Isomers Formed During Fish Oil Deodorization. Journal of Chromatography a 1129, 21-28. IF = 3.554.
48.Lagarde M, Astorg P, Guesnet P & Sebedio JL. (2006). Proceedings of the 7th Fatty Acid and Cell Signaling (FACS) workshop held in Paris on September 28-30, 2005. Prostaglandins Leukotrienes and Essential Fatty Acids 75, 127. IF = 2.261.
49. Rieu I, Balage M, Sornet C, Giraudet C, Pujos E, Grizard J, Mosoni L & Dardevet D. (2006). Leucine supplementation improves muscle protein synthesis in the elderly men independently of hyperaminoacidemia. Journal of Physiology 575, 305-315. IF = 4.407.
ACL, REV : Scientific review, peer-reviewed
50. Scalbert A, Brennan L, Fiehn O, Hankemeier T, Kristal BS, Van Ommen B, Pujos-Guillot E, Verheij E, Wishart D & Wopereis S. (2009). Mass-Spectrometry-Based Metabolomics: Limitations and Recommendations for Future Progress With Particular Focus on Nutrition Research. Metabolomics 5, 435-458. IF = 3.871.
51. Sebedio JL, Pujos-Guillot E & Ferrara M. (2009). Metabolomics in Evaluation of Glucose Disorders. Current Opinion in Clinical Nutrition and Metabolic Care 12, 412-418. IF = 4.291.
52. Sébédio JL. (2008). Composition of Milk Fat Introduction. Sciences Des Aliments 28, 5-11. IF = 0.171.
ACLN : Peer-reviewed articles in international and national journals not listed in international databases
53. Sébédio JL. (2007). Trans Fatty Acids: Nature, Origin and Impact on Health. Cahiers De Nutrition Et De Dietetique 42, 239-245.
54. Sébédio JL. (2007). Trans Fatty Acids: Nature, Origin and Impact on Health. Cahiers De Nutrition Et De Dietetique 42, 239-245.
VUP : Vulgarization articles
55. Pujos-Guillot E & Sébédio JL. (2009). Nouvelles approches métabolomiques en nutrition, apports et limites de la spectrométrie de masse. Spectra analyse 269, 41-45.
56. Sébédio J, Pujos-Guillot E & Martin JF (2009). La métabolomique : une nouvelle approche pour évaluer l’effet santé des aliments. Lettre scientifique de l’IFN n°139.
57. Sébédio JL. (2009). Nutrition et métabolomique. Cholé-Doc, 114.